2020, Volume 12, Issue 4

Exercise − A unique endogenous regulator of irisin, BDNF, leptin and cortisol against depression



Gilmara Gomes de Assis1, Paweł Cięszczyk1

1Gdansk University of Physical Education and Sport


Author for correspondence: Gilmara Gomes de Assis; Gdansk University of Physical Education and Sport; email: gilmara.gomesdeassis@awf.gda.pl


DOI: 10.29359/BJHPA.12.4.01

Full text

Abstract

Depression is the most prevalent stress-related disorder affecting the population world-wide with potential for an eminent increase after the 2020 pandemic. The mechanisms through which metabolism is involved in depression and stress disorders have been extensively investigated. However, their assessment using exogenous measures is a current limitation. Exercise, as is well reported in animal studies, exerts a critical regulatory influence on the main factors known to participate in these mechanisms. This overview describes the role of cortisol, leptin, irisin and BDNF in the exercise physiology and the known mechanism through which these factors act in anti-depressant mechanisms. Furthermore, the exercise is proposed as a clinical recommendation due to its effective and affordable character in treating depression for the sustainability of public health.


Key words: leptin, irisin, BDNF, metabolism, obesity


Cite this article as:

AMA:

Gomes de Assis G, Cięszczyk P. Exercise − A unique endogenous regulator of irisin, BDNF, leptin and cortisol against depression. Balt J Health Phys Activ. 2020;12(4):1-8. doi:10.29359/BJHPA.12.4.01

APA:

Gomes de Assis, G.., & Cięszczyk, P. (2020). Exercise − A unique endogenous regulator of irisin, BDNF, leptin and cortisol against depression. Balt J Health Phys Activ, 12(4), 1-8. https://doi.org/10.29359/BJHPA.12.4.01

Chicago:

Gomes de Assis, Gilmara , Cięszczyk Paweł. 2020. "Exercise − A unique endogenous regulator of irisin, BDNF, leptin and cortisol against depression". Balt J Health Phys Activ 12 (4): 1-8. doi:10.29359/BJHPA.12.4.01

Harvard:

Gomes de Assis, G.., and Cięszczyk, P. (2020). Exercise − A unique endogenous regulator of irisin, BDNF, leptin and cortisol against depression. Balt J Health Phys Activ, 12(4), pp.1-8. https://doi.org/10.29359/BJHPA.12.4.01

MLA:

Gomes de Assis, G.., and Cięszczyk, P. "Exercise − A unique endogenous regulator of irisin, BDNF, leptin and cortisol against depression." Balt J Health Phys Activ, vol. 12, no. 4, 2020, pp. 1-8. doi:10.29359/BJHPA.12.4.01

Vancouver:

Gomes de Assis G, Cięszczyk P. Exercise − A unique endogenous regulator of irisin, BDNF, leptin and cortisol against depression. Balt J Health Phys Activ 2020; 12(4): 1-8. Available from: doi:10.29359/BJHPA.12.4.01