2021, Volume 13, Issue 1

Purslane supplementation lowers oxidative stress, inflammatory and muscle damage biomarkers after high-intensity intermittent exercise in female runners

Anis Charkhi Sahl Abad¹, Amine Ghram², Rahman Soori¹, Ali Akbarnejad¹, Fatemeh Azizi Ghuchan³, Mohammad Mehdi Zare¹, Anthony C. Hackney⁴, Stephen J. Bailey<sup>5

1</sup>Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran
²Department of Cardiac Rehabilitation, Tehran Heart Center, Tehran University of Medical Sciences
³Department of Exercise Physiology, Bojnourd Branch, Islamic Azad University
⁴Department of Exercise & Sport Science, University of North Carolina
⁵School of Sport, Exercise and Health Sciences, Loughborough University


Author for correspondence: Amine Ghram; Department of Cardiac Rehabilitation, Tehran Heart Center, Tehran University of Medical Sciences; email: amineghram.110@ut.ac.ir

Full text

Abstract

Background: The aim of this study was to determine the effect of purslane supplementation on oxidative stress, inflammation and muscle damage biomarkers after completing high-intensity interval exercise (HIIE).

Methods: Nine healthy female runners completed a HIIE treadmill protocol comprising 1 min at 100% of the peak treadmill velocity attained in a preliminary exhaustive incremental treadmill test, interspersed by 1 min of passive recovery, until they had run for 2.5 km. Athletes repeated this test following 10 days of supplementation with 1000 mg per day of purslane.

Results: At baseline (i.e., absence of purslane supplementation) the HIIE protocol increased 9-HODE (p < 0.001), 13-HODE (p < 0.001), IL-17 (p < 0.001), TNF-α (p < 0.001), and LDH (p < 0.001). After purslane consumption, resting 9-HODE, 13-HODE, IL-17, TNF-α, and LDH were lowered (p < 0.001) and IL-10 was increased (p < 0.001) compared to before purslane supplementation. After purslane consumption and following the HIIE protocol, the responses of these biomarkers were lower compared to baseline (p < 0.001).

Conclusion: Ten days of purslane supplementation blunted the perturbation to biomarkers of oxidative stress, inflammation and muscle damage in female runners completing a HIIE protocol. 

Key words: ergogenic aid, nutraceutical, running exercise, exercise biochemistry